Top 13 Best Glutamine Supplements | Buoy (2025)

Glutamine is a non-essential amino acid that constitutes about 60% of the body’s glutamine supply and plays key roles in protein and nucleic acid synthesis, immune cell activation, and maintaining gastrointestinal health. Due to these benefits, glutamine is widely marketed as a supplement suitable for athletes, bodybuilders, and individuals with digestive issues.

It’s important to note that glutamine is available in several forms, including L-glutamine, glutamine peptides, and N-acetyl glutamine. Each form offers unique benefits and may be more suitable for specific needs.

Below, we’ve compiled a list of the best glutamine supplements on the market, evaluated based on potency, effectiveness, immune support, and customer reviews.

Top 3 Best Glutamine Supplements

1. Optimum Nutrition Glutamine 1000mg, 120 Capsules

2. NOW Supplements, L-Glutamine 500 mg

3. Evlution Glutamine5000

If you are in search of a reliable supplement, that could help the muscles grow and recover, you should consider this one. This one brings 1000mg of pure L-glutamine in just two capsules which makes it one of the best options you can get.

A key feature of Optimum Nutrition Glutamine is that it contains glutamine, which is the most prevalent amino acid in the human body. Notably, Optimum Nutrition Glutamine 1000mg can help support weight training while also promoting muscle recovery. This holds much importance, especially for those who do vigorous exercise for long durations of time.

Although this supplement is safe for the majority of the population, it is noteworthy that the product should be stored properly, as the influence of heat or sunlight on the capsules may lead to their melting or deterioration.

NOW Supplements L-Glutamine 500 mg is especially good for those who want a top-tier glutamine supplement used to boost immune function and help with nitrogen balance. The capsules are easy to swallow, gluten-free, lactose-free, and are made without eggs or soy, and are vegetarian and vegan which can also be considered as advantages.

In terms of the product itself, it is sensitive to heat and direct sunlight and may melt or become damaged; thus, it is recommended that customers make arrangements to ensure that someone is at home to receive the product when it is delivered. A disadvantage that is worth noting is that the capsules are quite large and may be unsuitable with people who do not like large pills.

In conclusion, NOW Supplements L-Glutamine 500 mg is one of the best supplements that can help boost the immune system as well as maintain nitrogen balance.

If you want something more powerful and efficient, you should consider Evlution Nutrition Glutamine5000. This supplement is beneficial for most people especially those who need to have their muscles built to help in their recovery after working out.

It provides the user with 5 grams of pure plant-based nitric oxide powder that will enable them to accomplish their objectives. Also, it aids in quicker muscle recovery and helps in muscle building because of the amino acid. Manufactured in the United States at a cGMP facility, this is definitely one of the best amino acid-based post-workout supplements you can get.

Overall, Evlution Glutamine5000 has a good formula – If you want a high-quality glutamine supplement that is good for your money, this supplement should be on your list. It is natural, free from any additives and preservatives, and is compounded only with lab-tested superior-grade components and materials.

Nutricost L-Glutamine Powder is also recommended if you want to buy a top-notch glutamine supplement. It is a product that provides support for the digestive process, immune system, weight, and brain functions should consider. It is in a powdered form, that can easily be added to any preferred beverage or a smoothie and has no content of gluten, soy, and GMOs.

There is one feature of the supplement that I would like to raise concern and that is the high amount of L-Glutamine Powder per serving. This product contains 5000mg of L-Glutamine Powder and thus, it is evident that one will be getting enough dose of this non-essential amino acid.

Finally, Nutricost L-Glutamine Powder does not have Prop 65 warnings and is made in a GMP-compliant FDA-registered facility. This implies that you can be assured and confident that the product has gone through the standard measures of quality and safety.

Honestly, the unflavored powder may be less tastier compared to other packed powdered milk but it is best for those who do not want added conserve and sugar. Some users have noted downsides to the operation of the container, for instance, the lid can be challenging to open or close and when the container falls over the powder spills out.

All things considered, if you are in the market for an extremely reputable glutamine supplement that is absolutely vegetarian, gluten-free, and, most importantly, made in a very highly standard and safe manner, then Nutricost L-Glutamine Powder would ideally fit the bill.

The Life Extension Glutamine Supplement is one of the best products you could consider if you wish to buy a top-of-the-range glutamine supplement.

We recommend this glutamine supplement for optimal muscle bulk, immunity and digestion, and adequate energy when under stress. It is manufactured from pure powder derived from L-glutamine which is not encased in a complex structure and does not contain gluten or GMOs.

The inclusion of muscle tissues and antioxidant properties promote the strengthening of anti-oxidative stress. Furthermore, Life Extension also pays a lot of attention to top-of-the-line ingredients and maintaining the quality of those ingredients as well.

That is why, while this supplement may not be recommended for everyone, for anyone willing to boost their activities and support it with the highest quality glutamine, this product is perfect.

If you are sick of taking synthetic supplements, you will love REVIVE Gut L-Glutamine Powder MD, as it is natural and can support your health. This supplement is rich in L-Glutamine which plays a crucial role in supporting muscle recovery and also reduces muscle soreness, improve your immunity, and play a big role in maintaining a healthy gut.

What most people will like about it is that it is vegan, gluten-free, and soy-free. It is perfect for anyone interested in a natural way to enhance his or her performance in day-to-day activities. Also, it is quite convenient to use, and it has a very mild and blendable mix; therefore, you can just apply it to your schedule.

What makes this supplement even better is that it contains effective substances and does not contain any additives such as Proprietary blends, colors, or preservatives.

In conclusion, for those who are looking for a product that helps to improve the health of the body on a broad level, this is the best choice.

Thorne L-Glutamine is a highly effective and pure amino acid that works wonders in improving the health of your gut, immune system, and muscles. This supplement, well-known for its efficacy and extraordinary concentration, offers 5 grams of L-glutamine per portion, thus enabling anyone seeking to enhance their fitness and well-being.

First of all, its advantage is that it does not contain any synthetic additives or allergens, which means that it is a natural, science-backed option that can be helpful for different dietary preferences. The brand Thorne is well-established in the supplement market, and each batch of the product goes through lab testing to guarantee its quality and efficacy to consumers.

An added advantage of using this product is that it helps boost digestion and this is very important for people with digestion problems or for those who frequently suffer from bloating or such distress. The fact that it comes in a powder form that can be blended with shakes or diluted with water has also been regarded as an added bonus.

Still, some users might consider the taste less than exciting or even off-putting for those who do not have a flavored drink to wash it down with. Also, the supplement is not hazardous to health, but users with sensitive stomachs to L-glutamine may develop slight digestive issues.

All in all, we would classify it as good for anyone who is looking for a great product that would provide them with L-glutamine.

This product from Naked Nutrition comes with additional L-Arginine and Vitamin B, making it a vegan product with an optimal formula that targets muscle recovery. This supplement has only L-glutamine as the component, which makes the product pure from any fillers, flavors, or anything extra. This flavor offers 5 grams per serving, which may make this a simple choice for athletes and others in search of an uncomplicated recovery supplement.

Comes in a BPA-free package which aligns with Naked Nutrition’s goal and philosophy of providing the highest quality and purity to the consumers. The high dose per serving also makes it possible to take supplements without having to take a lot of the powder.

Nonetheless, it comes with no flavors which might be disadvantageous for individuals who prefer flavored supplements, and since it dissolves well in liquid, a shaker or blender is recommended to prevent lumping. The only potential drawback that I can see is the lack of pre-measured scoops: it may take a little more effort to get the portions right.

L-Glutamine Supplement from Pure Encapsulations is a perfect dietary supplement if you need something to boost your immunity and the function of your digestive system, maintain and build muscles, and stabilize your metabolic process.

Before deciding to purchase the product, a consumer should consider the list of Pure Encapsulations L-Glutamine Supplement ingredients, as well as two more pointers of a high-quality supplement that does not contain allergens, artificial or unnecessary substances, or genetically modified elements. The supplement is designed to primarily support the digestive system, lean muscle gain, and general wellness of the body.

Overall, Pure Encapsulations L-Glutamine Supplement is one of the best recommendations that you can turn to in case you feel you need an additional aid for a properly functioning digestive system. Due to the high-quality ingredients that are used for the preparation of this product, and the correct processing, you will be in a position to get the best results as you desire.

Moreover, Pure Encapsulations L-Glutamine Supplement has no side effects despite its numerous health benefits, which makes this product free from allergens and ideal for those who have allergic reactions to some products.

In conclusion, L-glutamine is a critical amino acid that plays an essential role in managing various health issues, including digestion, metabolism, muscles, and the immune system; Pure Encapsulations L-Glutamine Supplement is highly recommended for anyone who wants to boost their glutamine intake and improve their overall health.

BULKSUPPLEMENTS.COM L-Glutamine Powder is a rather effective supplement that could be used for encouraging muscle recovery and providing healthy digestion. It is gluten-free, contains no soy product, does not include any dairy products, and is free from any kind of added sugar which makes it ideal for the active healthy lifestyle person. Also, the supplement can be dissolved in any drink of your desire or water alone since it dissolves easily.

We also must point out the effectiveness of this supplement in helping muscles recover, and that is a big plus for anyone who exercises vigorously. L-glutamine is one of the conditionally essential amino acids that can potentially assist your muscle tissues in recuperating more effectively. Including this supplement in one’s diet plan will complement the BCAA supplements so that you can effectively meet all your activities both during the day and beyond. Furthermore, this product may help you train harder for longer periods for those of you concerned with sheer muscle mass accumulation.

Yet another advantage of this supplement is that it facilitates beneficial bacteria in the human gastrointestinal tract. L-glutamine is a key component of the intestinal lining mucosa which is important for the proper functioning of the healthy bacteria that make up the gut flora. In our opinion, it would be ideal for people who want to maintain the health of their gut and promote better absorption of nutrients.

This supplement has practical advantages but to some people, it may cause unpleasant feelings in the stomach. Moreover, users may complain of bitter tastes that are due to the presence of different chemicals that are found in the leaves. Lastly, the packaging is one disadvantage in the sense that it may not be their choice to have a book instead of a hard-packaged product.

Overall, BULKSUPPLEMENTS.COM L-Glutamine Powder is the perfect product to try out. It is quality Strepsils, gluten-free, and easily soluble with any drink of your preference in a single Glass.

Needless to say, if money is not a constraint and you are looking for a pure L-glutamine supplement, then Pure Encapsulations L-Glutamine Powder should not be overlooked.

Since this supplement targets the digestion process, its goal is to strengthen the mucous layer of the gastrointestinal tract. It also serves the aim of maintaining lean muscles, particularly during situations when the metabolic rate is highly stressed. Also, L-glutamine, the free form of Glutamine, being utilized by the body for its various aims like tissue reinforcement and support for the gastrointestinal tract.

Quality is one of the most standout features of this supplement. The ingredients are purchased from accredited suppliers and the product is prepared in such a manner that they are highly effective and pure. It is also free from allergens such as Gluten, Free from artificial/ Added/ Unnecessary Ingredients, and GMOs.

Nevertheless, it has no flavor at all, which might be a drawback to some. Also, the price is higher than that of the different brands of the same product available in the supermarket. Lastly, some users have said that the powder does not dissolve well in cold water or any cold beverages.

In conclusion, if you need a premium L-glutamine supplement with quality capsules for the health of gastrointestinal lining, lean muscle mass and other bodily functions, the Pure Encapsulation L-Glutamine Powder is one worth looking at.

If you are searching for a glutamine supplement that you can use for muscle recovery and to boost endurance, MuscleTech’s 100% Glutamine Powder is a reliable product.

Glutamine Powder by MuscleTech comes in a formula that will help you replace the lost glutamine in your muscles much faster than you can imagine after rigorous exercises. It has no smell and is not grainy but has a powdered form, which makes it blend well with other products that we intend to add to it.

However, the supplement should not be exposed to direct heat or sunlight, and also the short scoop can lead to difficulty in accessing the powder. Other complications that were reported by customers include the fact that the product came with some bad side effects, which we did not experience.

All in all, if you are in search of a good glutamine supplement and are not hesitant to take certain measures to preserve the product, MuscleTech’s Glutamine Powder could be just what the muscle and endurance trainer ordered.

If you are interested in purchasing a top-notch glutamine supplement NOW Sports L-Glutamine Double Strength seems like a viable option to consider.

NOW Sports L-Glutamine Double Strength is an ideal supplement that has been subjected to rigorous experimentation and analysis regarding content and efficacy. It comes with a concentrated form of Glutamine, where each capsule contains 1000mg of this compound, whereas the most common ones contain merely 500mg. This supplement is potent in nitrogen accumulation and immune strength, a must-buy product especially for athletes and anyone who spends several hours on regular activities.

The only weakness that we found regarding this supplement is that it may become soft or even change its shape when exposed to heat or direct sunlight, so it has to be stored in a dry area. Some people might not feel any effects of the supplement since the efficacy varies.

All in all, NOW Sports L-Glutamine Double Strength is a great product perfect for any athlete who is seriously considering taking glutamine supplements.

Frequently Asked Questions

1. What is the best form of glutamine to take?

The best known and most used is L-glutamine which is considered the most active form of this amino acid. However, there are also other forms, for instance, glutamine peptides and N-acetyl L-glutamine that are present in subtlety different forms. Specifically, when it comes to choosing glutamine, one should consult a healthcare provider to decide on the form of glutamine that is right for him or her.

2. What is a good brand of L-glutamine?

Some popular brands of L-glutamine supplements include Now, Nature’s Own, Platinum Performance, and MetabolicResponses. These brands that can be easily found in the market include Optimum Nutrition, Jarrow Formulas, and NOW Sports. The brand chosen should be one that is not only credible but also should have much positive feedback from previous clients.

3. What happens if I take L-glutamine every day?

Daily administration of L-glutamine within the recommended daily allowance is not toxic and there are uncommon side effects associated with the supplement. There’s some evidence that it could help boost immunity digestive health and muscle recovery. That being said, it is highly recommended that one obtain professional medical consultation prior to incorporating any dietary supplements into their lifestyle.

4. Is it better to take glutamine or L-glutamine?

Among all the forms of glutamine, L-glutamine is the most commonly used form in supplements and is regarded as more effective compared to others. However, in order, there are certain people who may find other types like glutamine peptides or N-acetyl L-glutamine more suitable.

5. What are the benefits of taking a glutamine supplement?

Glutamine supplements may help support immune function, gut health, and muscle recovery. It may also help reduce muscle soreness and improve exercise performance. However, more research is needed to fully understand the benefits of glutamine supplementation.

6. Can glutamine supplements help with muscle recovery?

Supplements containing glutamine may be beneficial in recovery from muscle damage as it has been shown to decrease muscle tenderness and increase protein synthesis. Nevertheless, it must be asserted that the use of glutamine supplements should not be relied upon to replace rest and recuperation. Before introducing any new supplement regime, one is advised to seek medical advice from a qualified medical attendant.